Medicube TXA NIACINAMIDE 15% SERUM

Medicube TXA Niacinamide 15% Serum It is an intensive treatment scientifically formulated for the comprehensive management of dermal and epidermal hyperpigmentation, with a strong foundation in contemporary dermatological literature. Its therapeutic action is based on a synergy between two key ingredients: tranexamic acid (TXA) at 5% and niacinamide at 15%, both clinically relevant concentrations.

Mechanism of action:

• Tranexamic acid (TXA)acts as an inhibitor of ultraviolet light-induced plasminogen activation in keratinocytes, interfering with the signaling pathway that leads to excessive melanin production. Its topical use has been shown to be effective in reducing melasma and post-inflammatory hyperpigmentation by indirectly blocking melanocyte activation.

• Niacinamide (vitamin B3): modulates the transfer of melanosomes from melanocytes to keratinocytes, thereby reducing the visibility of pigmentation. Additionally, it regulates ceramide synthesis and improves the epidermal barrier, with an anti-inflammatory effect mediated by the inhibition of cytokine release such as IL-1 and TNF-.

• Multilayer hyaluronic acid (10 layers)Provides multi-layer structural hydration that promotes tissue repair, optimizes the dermal microenvironment, and improves the bioavailability of active ingredients.

• Panthenol (provitamin B5) and betaineThey act as osmolytes and epithelial agents, stabilizing the hydrolipidic barrier and reducing transepidermal water loss (TEWL).

• Coralline moss extract: offers complementary antioxidant action, protecting the skin from oxidative stress and environmental aggressors.